Across TCGA patient cohorts, BAZ1A mutation is significantly associated with the RNA expression of many other genes, with 3,459 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ1A-associated genes across cancer lineages are MRPL22, CENPH, and BUB3. Each is linked with BAZ1A in more than 3 cancer types. Because this analysis shows association rather than direction, both BAZ1A-to-partner and partner-to-BAZ1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ1A→partner) and Y-score (partner→BAZ1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL22 →	+0.271	+2.328	<.001	<.001	3	4
UCEC	CENPH →	+0.612	+2.010	<.001	<.001	3	3
UCEC	BUB3 →	+0.443	+2.212	<.001	<.001	3	3
COAD	SKA1 →	+0.865	+3.584	<.001	.002	3	3
UCEC	SEC13 →	+0.337	+2.169	<.001	<.001	3	3
UCEC	MFSD12 →	+0.388	+2.032	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,459 associations by consensus.

Exploration

BAZ1A survival (RNA) · tumor vs normal (RNA) · all BAZ1A data types