BAZ1A

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BAZ1A mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAZ1A-associated genes across cancer lineages are Caspase-7-cleavedD198, JNK_pT183_Y185, and Cyclin-E2. Each is linked with BAZ1A in more than 2 cancer types. Because this analysis shows association rather than direction, both BAZ1A-to-partner and partner-to-BAZ1A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAZ1A→partner) and Y-score (partner→BAZ1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+1.419+2.593<.001.00633
UCECJNK_pT183_Y185 →-0.151-1.765.004.01333
UCECCyclin-E2 →+0.140+2.097.008.00333
LUSCTFRC →+0.750+3.179.027.01032
COADeIF4E →+0.188+3.012.011.01832
COADGAPDH →+0.421+1.882.047.03132
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration