BATF2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BATF2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BATF2-associated genes across cancer lineages are ASB10, TERB2, and UBQLN3. Each is linked with BATF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BATF2-to-partner and partner-to-BATF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB10 grouped by BATF2-low versus BATF2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BATF2→partner) and Y-score (partner→BATF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINASB10 →+0.033+4.467<.001.00431
SKINTERB2 →+0.012+4.415<.001.00731
SKINUBQLN3 →+0.012+4.415<.001.00731
SKINOR52E4 →+0.035+4.273<.001.00631
SKINTMPRSS12 →+0.084+4.930<.001.00131
SKINAMY1A →+0.019+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ASB10 by BATF2 expression — SKIN

Box plot of ASB10 in BATF2-low vs BATF2-high samples in SKIN.

Explore this box plot interactively →

Exploration