BATF

Across TCGA patient cohorts, BATF mutation is significantly associated with the RNA expression of many other genes, with 209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BATF-associated genes across cancer lineages are OFD1P2Y, MIR6851, and P3R3URF-PIK3R3. Each is linked with BATF in more than 1 cancer types. Because this analysis shows association rather than direction, both BATF-to-partner and partner-to-BATF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OFD1P2Y grouped by BATF-low versus BATF-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BATF→partner) and Y-score (partner→BATF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OFD1P2Y →	+0.108	+5.469	<.001	.002	3	2
SKCM	MIR6851 →	+0.758	+4.440	<.001	.006	3	1
SKCM	P3R3URF-PIK3R3 →	+0.041	+5.199	<.001	.003	3	1
UCEC	PGAP2 →	+0.433	+3.475	.007	.002	3	1
UCEC	ME3 →	-0.858	-3.459	<.001	.005	3	1
UCEC	SAR1B →	+0.565	+2.609	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 209 associations by consensus.

OFD1P2Y by BATF expression — SKCM

Explore this box plot interactively →