BATF

Across TCGA patient cohorts, BATF mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BATF-associated genes across cancer lineages are MEK1, eIF4E, and JNK2. Each is linked with BATF in more than 1 cancer types. Because this analysis shows association rather than direction, both BATF-to-partner and partner-to-BATF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by BATF-low versus BATF-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BATF→partner) and Y-score (partner→BATF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.453	+3.169	.013	.019	3	2
UCEC	eIF4E →	+0.242	+3.000	.022	.036	2	2
UCEC	JNK2 →	+0.288	+2.834	.003	.034	3	1
UCEC	MSH2 →	-0.274	-2.321	.018	.035	3	1
UCEC	Annexin-1 →	+0.913	+3.189	<.001	.010	3	1
UCEC	Axl →	-0.242	-3.285	.025	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MEK1 by BATF expression — UCEC

Explore this box plot interactively →