BARHL2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BARHL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,661 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BARHL2-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Positive regulation of cell cycle G2/M phase transition, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with BARHL2 in more than 13 cancer types. Because this analysis shows association rather than direction, both BARHL2-to-partner and partner-to-BARHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by BARHL2-low versus BARHL2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL2→partner) and Y-score (partner→BARHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADPositive regulation of mitotic cell cycle →+0.045+0.094<.001<.001314
STADPositive regulation of cell cycle G2/M phase transition →+0.041+0.096<.001<.001313
STADMicrotubule cytoskeleton organization involved in mitosis →+0.055+0.087<.001<.001313
STADPurine nucleoside monophosphate biosynthetic process →+0.051+0.088<.001<.001313
STADDNA unwinding involved in DNA replication →+0.044+0.077<.001<.001313
SCLCSpindle assembly →+0.098+2.063<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,661 associations by consensus.

Positive regulation of mitotic cell cycle by BARHL2 expression — STAD

Box plot of Positive regulation of mitotic cell cycle in BARHL2-low vs BARHL2-high samples in STAD.

Explore this box plot interactively →

Exploration