BARHL2

Across TCGA patient cohorts, BARHL2 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BARHL2-associated genes across cancer lineages are INPP4B, PCNA, and TFRC. Each is linked with BARHL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARHL2-to-partner and partner-to-BARHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by BARHL2-low versus BARHL2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL2→partner) and Y-score (partner→BARHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.321	-2.700	.008	.006	3	2
UCEC	PCNA →	+0.220	+2.807	.006	.003	3	2
UCEC	TFRC →	+0.538	+2.459	.006	.018	3	2
UCEC	ATM →	-0.551	-2.169	.001	.003	3	2
UCEC	Caspase-7-cleavedD198 →	+0.527	+2.720	.018	.003	3	2
UCEC	Cyclin-E1 →	+0.498	+2.169	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

INPP4B by BARHL2 expression — UCEC

Explore this box plot interactively →