BARHL2

Across TCGA cell cohorts, BARHL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,715 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BARHL2-associated GO terms across cancer lineages are Positive regulation of sodium ion transmembrane transport, Regulation of sodium ion transport, and Positive regulation of sodium ion transport. Each is linked with BARHL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both BARHL2-to-partner and partner-to-BARHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sodium ion transmembrane transport grouped by BARHL2-low versus BARHL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL2→partner) and Y-score (partner→BARHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of sodium ion transmembrane transport →	-0.223	-2.406	<.001	<.001	3	6
BONE	Regulation of sodium ion transport →	-0.141	-2.947	<.001	<.001	3	6
BONE	Positive regulation of sodium ion transport →	-0.229	-3.002	<.001	<.001	3	5
BONE	Regulation of protein localization to membrane →	-0.078	-2.476	<.001	<.001	3	5
SOFT_TISSUE	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.051	+0.164	.008	.006	3	5
BONE	Intracellular calcium ion homeostasis →	-0.075	-2.713	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,715 associations by consensus.

Positive regulation of sodium ion transmembrane transport by BARHL2 expression — BONE

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