BARHL2

Across TCGA cell cohorts, BARHL2 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BARHL2-associated genes across cancer lineages are OR2T35, CST4, and GTSF1L. Each is linked with BARHL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARHL2-to-partner and partner-to-BARHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T35 grouped by BARHL2-low versus BARHL2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL2→partner) and Y-score (partner→BARHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	OR2T35 →	+0.086	+4.807	<.001	.006	3	1
LUNG_SCLC	CST4 →	+0.672	+3.762	<.001	.003	3	1
LUNG_SCLC	GTSF1L →	+0.277	+3.256	<.001	.005	3	1
LUNG_SCLC	SPAG11B →	+1.027	+4.578	.002	<.001	3	1
LUNG_SCLC	TECRL →	+0.183	+3.762	.003	.003	3	1
LUNG_SCLC	OR13C5 →	+0.029	+3.232	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

OR2T35 by BARHL2 expression — BLOOD_Myeloma

Explore this box plot interactively →