BARHL1

Across TCGA pan-cancer cohorts, BARHL1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated BARHL1 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher BARHL1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BARHL1 expression acts as an unfavorable survival marker.

ESCA, BLCA, and COAD are the cancer types where BARHL1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.102	0.703	<.001	36	view →
BLCA	OS	Median	IV	0.130	0.599	.002	24	view →
COAD	OS	Median	III,IV	0.208	0.791	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

BARHL1–ESCA (OS)

Open the ESCA breakdown →