BARHL1

Across TCGA cell cohorts, BARHL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,506 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BARHL1-associated GO terms across cancer lineages are Regulation of protein localization to centrosome, Constitutive heterochromatin formation, and Epigenetic regulation of gene expression. Each is linked with BARHL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both BARHL1-to-partner and partner-to-BARHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to centrosome grouped by BARHL1-low versus BARHL1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL1→partner) and Y-score (partner→BARHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of protein localization to centrosome →	+0.069	+0.023	.002	.002	3	8
BONE	Constitutive heterochromatin formation →	+0.075	+0.018	.003	.004	3	7
BONE	Epigenetic regulation of gene expression →	+0.059	+0.022	.001	<.001	3	7
BONE	Positive regulation of DNA metabolic process →	+0.063	+0.019	.002	.003	3	7
BLOOD_Lymphoma	Oocyte growth →	+0.121	+0.029	.004	<.001	3	6
BONE	Pre-mRNA catabolic process →	+0.193	+0.017	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,506 associations by consensus.

Regulation of protein localization to centrosome by BARHL1 expression — PANCREAS

Explore this box plot interactively →