BARHL1

Across TCGA cell cohorts, BARHL1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BARHL1-associated genes across cancer lineages are TGM6, NKX2-6, and TLE7. Each is linked with BARHL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BARHL1-to-partner and partner-to-BARHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM6 grouped by BARHL1-low versus BARHL1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BARHL1→partner) and Y-score (partner→BARHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TGM6 →	+0.043	+5.977	<.001	.001	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TGM6 by BARHL1 expression — SOFT_TISSUE

Explore this box plot interactively →