BAP1

Across TCGA patient cohorts, BAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,937 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BAP1-associated proteins across cancer lineages are HSPA5, HSP90B1, and PRDX4. Each is linked with BAP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BAP1-to-partner and partner-to-BAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAP1 versus HSPA5 in CCRCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BAP1→partner) and Y-score (partner→BAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HSPA5 →	-0.282	-0.257	<.001	.001	3	6
GBM	HSP90B1 →	-0.385	-0.321	<.001	<.001	3	6
BRCA	PRDX4 →	-0.529	-0.553	<.001	<.001	3	5
GBM	RBM15B →	+0.246	+0.222	<.001	<.001	3	5
LUAD	CRELD2 →	-0.511	-0.351	<.001	<.001	3	5
GBM	RBM5 →	+0.285	+0.342	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,937 associations by consensus.

BAP1 vs HSPA5 — CCRCC

Explore this scatter interactively →