BAP1

Across TCGA patient cohorts, BAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,876 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BAP1-associated genes across cancer lineages are ZNF670-ZNF695, NUF2, and FAM189B. Each is linked with BAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BAP1-to-partner and partner-to-BAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BAP1 versus ZNF670-ZNF695 in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAP1→partner) and Y-score (partner→BAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF670-ZNF695 →	+0.839	+0.296	<.001	<.001	3	4
LSCC	NUF2 →	+1.257	+0.252	<.001	<.001	3	4
HNSC	FAM189B →	+0.635	+0.209	<.001	<.001	3	4
BRCA	SEH1L →	+0.522	+0.166	<.001	.003	3	4
BRCA	PALMD →	-0.957	-0.184	<.001	.002	3	4
BRCA	ZCCHC24 →	-1.118	-0.177	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,876 associations by consensus.

BAP1 vs ZNF670-ZNF695 — UCEC

Explore this scatter interactively →