BAP1

Across TCGA cell cohorts, BAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,432 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BAP1-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Nucleocytoplasmic transport, and Establishment of mitotic spindle localization. Each is linked with BAP1 in more than 18 cancer types. Because this analysis shows association rather than direction, both BAP1-to-partner and partner-to-BAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by BAP1-low versus BAP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BAP1→partner) and Y-score (partner→BAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.091	+0.512	.008	.005	3	19
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.083	+0.979	<.001	<.001	3	18
SOFT_TISSUE	Establishment of mitotic spindle localization →	+0.129	+0.733	.001	<.001	3	18
SOFT_TISSUE	Microtubule polymerization →	+0.117	+0.822	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.084	+0.923	<.001	<.001	3	18
SOFT_TISSUE	Microtubule nucleation →	+0.126	+0.742	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,432 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by BAP1 expression — BONE

Explore this box plot interactively →