BANP

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BANP mutation is significantly associated with the drug of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BANP-associated genes across cancer lineages are Nelarabine, Dacarbazine, and TL-2-105. Each is linked with BANP in more than 1 cancer types. Because this analysis shows association rather than direction, both BANP-to-partner and partner-to-BANP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nelarabine grouped by BANP-low versus BANP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BANP→partner) and Y-score (partner→BANP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINENelarabine →+0.284+2.649.031.04631
LARGE_INTESTINEDacarbazine →+0.280+2.777.045.03831
LARGE_INTESTINETL-2-105 →+0.474+2.652.015.04531
LARGE_INTESTINEQuizartinib →+0.491+2.652.001.04531
LARGE_INTESTINEJNJ38877605 →+0.376+2.786.029.03731
LARGE_INTESTINESU11274 →+0.483+2.652.019.04531
Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Nelarabine by BANP expression — LARGE_INTESTINE

Box plot of Nelarabine in BANP-low vs BANP-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration