BANF1

Across TCGA pan-cancer cohorts, BANF1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated BANF1 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BANF1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated BANF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

HNSC, LUAD, and CCRCC are the cancer types where BANF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.189	1.000	.008	36	view →
LUAD	DFS	Tertile	III,IV	0.250	0.737	.001	32	view →
CCRCC	DFS	Median	III,IV	0.772	0.402	.002	23	view →
PDAC	DFS	Median	All	0.839	0.611	.011	13	view →
GBM	OS	Tertile	All	0.675	0.342	.026	2	view →
LSCC	DFS	Tertile	All	0.999	0.862	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

BANF1–HNSC (OS)

Open the HNSC breakdown →