BANF1

Across TCGA cell cohorts, BANF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,609 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BANF1-associated GO terms across cancer lineages are Regulation of attachment of mitotic spindle microtubules to kinetochore, Positive regulation of attachment of mitotic spindle microtubules to kinetochore, and Double-strand break repair via break-induced replication. Each is linked with BANF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both BANF1-to-partner and partner-to-BANF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of attachment of mitotic spindle microtubules to kinetochore grouped by BANF1-low versus BANF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BANF1→partner) and Y-score (partner→BANF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.152	+0.997	.002	<.001	3	17
SOFT_TISSUE	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.162	+0.600	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.214	+1.577	.001	<.001	3	15
BLOOD_Lymphoma	Mitotic metaphase chromosome alignment →	+0.107	+0.811	<.001	<.001	3	14
SOFT_TISSUE	Spindle elongation →	+0.219	+0.565	.001	.003	3	13
URINARY_TRACT	DNA replication checkpoint signaling →	+0.110	+0.805	.005	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,609 associations by consensus.

Regulation of attachment of mitotic spindle microtubules to kinetochore by BANF1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →