BAK1P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BAK1P2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BAK1P2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher BAK1P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BAK1P2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and ESCA show a favorable association.

LUSC, UCEC, and STAD are the cancer types where BAK1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCDFSTertileIII,IV0.0100.754<.00136view →
UCECDFSMedianAll0.7860.867.00432view →
STADDFSQuartileIII,IV0.4560.638.00831view →
BRCAOSMedianII,III,IV0.6620.481.00426view →
LUADOSTertileAll0.2030.390.01424view →
CESCOSTertileIII,IV0.4530.786.01424view →
LAMLDFSMedianAll0.2330.514.01824view →
ESCADFSTertileIII,IV0.5490.245.00617view →
UCSDFSTertileAll0.3730.598.02816view →
KIRPDFSMedianAll0.3330.698<.00115view →
LIHCOSTertileII,III,IV0.1280.623.01015view →
UVMOSTertileAll0.4000.706.03712view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BAK1P2–LUSC (DFS)

Kaplan–Meier survival curve for BAK1P2 RNA-high vs -low samples in LUSC.

Open the LUSC breakdown →

Exploration