BAIAP2L2

Across TCGA patient cohorts, BAIAP2L2 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAIAP2L2-associated genes across cancer lineages are cIAP, FoxM1, and Notch1. Each is linked with BAIAP2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BAIAP2L2-to-partner and partner-to-BAIAP2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cIAP grouped by BAIAP2L2-low versus BAIAP2L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAIAP2L2→partner) and Y-score (partner→BAIAP2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cIAP →	+0.184	+3.348	.010	.005	3	2
UCEC	FoxM1 →	+0.400	+3.321	.003	.010	3	1
UCEC	Notch1 →	+0.250	+3.321	<.001	.010	3	1
UCEC	STAT3_pY705 →	-0.510	-2.999	<.001	.035	3	1
UCEC	VHL →	-1.279	-3.000	<.001	.036	3	1
UCEC	4E-BP1 →	+0.428	+2.837	.002	.035	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

cIAP by BAIAP2L2 expression — UCEC

Explore this box plot interactively →