BAIAP2L1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BAIAP2L1 Mutation is linked to patient survival in 9 of 34 cancer types, making it a survival-associated BAIAP2L1 data layer compared with 26 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BAIAP2L1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated BAIAP2L1 expression acts as an unfavorable survival marker.

HNSC, LUAD, and BLCA are the cancer types where BAIAP2L1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSMedianIII,IV0.0500.611<.00142view →
LUADOSMedianAll0.2910.837<.00131view →
BLCADFSMedianIII,IV0.0940.489.0059view →
LIHCOSMedianAll0.1440.688.0139view →
SARCOSMedianAll0.2380.826.0016view →
PRADDFSMedianAll0.0850.774<.0016view →
ESCADFSMedianII,III,IV0.1860.525.0196view →
STADDFSMedianAll0.2310.632.0473view →
SKCMOSMedianAll0.3330.780.0463view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

BAIAP2L1–HNSC (DFS)

Kaplan–Meier survival curve for BAIAP2L1 mutant vs wild-type samples in HNSC.

Open the HNSC breakdown →

Exploration