BAIAP2

Across TCGA patient cohorts, BAIAP2 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAIAP2-associated genes across cancer lineages are eIF4E, FOXO3a_pS318_S321, and PCNA. Each is linked with BAIAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BAIAP2-to-partner and partner-to-BAIAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by BAIAP2-low versus BAIAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAIAP2→partner) and Y-score (partner→BAIAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.194	+3.920	.001	<.001	3	2
UCEC	FOXO3a_pS318_S321 →	-0.101	-1.767	.004	.001	3	2
UCEC	PCNA →	+0.241	+2.662	<.001	<.001	3	2
UCEC	PEA-15_pS116 →	+0.224	+1.222	.025	.032	3	2
UCEC	STAT3_pY705 →	-0.316	-1.398	<.001	.004	3	2
UCEC	ATM →	-0.581	-2.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

eIF4E by BAIAP2 expression — UCEC

Explore this box plot interactively →