BAHD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BAHD1 mutation is significantly associated with the RNA expression of many other genes, with 4,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAHD1-associated genes across cancer lineages are WDR5, GLRX3, and RIOK1. Each is linked with BAHD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BAHD1-to-partner and partner-to-BAHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR5 grouped by BAHD1-low versus BAHD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAHD1→partner) and Y-score (partner→BAHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECWDR5 →+0.456+3.021<.001<.00133
UCECGLRX3 →+0.434+2.243<.001.00533
UCECRIOK1 →+0.357+2.230.008.00633
BRCARNU6-65P →+0.307+8.055<.001.00733
UCECBIRC5 →+0.578+1.880.005.00433
BLCAST13P14 →+0.043+3.236<.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,393 associations by consensus.

WDR5 by BAHD1 expression — UCEC

Box plot of WDR5 in BAHD1-low vs BAHD1-high samples in UCEC.

Explore this box plot interactively →

Exploration