BAHD1

Across TCGA cell cohorts, BAHD1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAHD1-associated genes across cancer lineages are NKX2-6, TLE7, and CWH43. Each is linked with BAHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BAHD1-to-partner and partner-to-BAHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKX2-6 grouped by BAHD1-low versus BAHD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAHD1→partner) and Y-score (partner→BAHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	CWH43 →	+0.948	+3.491	<.001	.004	3	1
LARGE_INTESTINE	GRM1 →	+0.029	+3.750	.006	.007	3	1
LARGE_INTESTINE	FAM153B →	+0.541	+3.618	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

NKX2-6 by BAHD1 expression — BLOOD_Leukemia

Explore this box plot interactively →