BAHCC1

Across TCGA patient cohorts, BAHCC1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAHCC1-associated genes across cancer lineages are Cyclin-B1, PCNA, and Caspase-7-cleavedD198. Each is linked with BAHCC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BAHCC1-to-partner and partner-to-BAHCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by BAHCC1-low versus BAHCC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAHCC1→partner) and Y-score (partner→BAHCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.494	+2.415	.003	.002	3	4
COAD	PCNA →	+0.240	+1.815	.009	.016	3	3
COAD	Caspase-7-cleavedD198 →	+1.130	+3.601	<.001	.001	3	3
COAD	Claudin-7 →	+0.570	+1.815	.021	.016	3	3
COAD	INPP4B →	-0.379	-2.459	.006	.018	3	2
COAD	Lck →	+0.352	+1.832	.001	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Cyclin-B1 by BAHCC1 expression — UCEC

Explore this box plot interactively →