BAGE2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BAGE2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BAGE2 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BAGE2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BAGE2 expression acts as an unfavorable survival marker.

HNSC and LUSC are the cancer types where BAGE2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.1150.768<.00148view →
LUSCDFSMedianII,III,IV0.1350.663.0156view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration