Across TCGA patient cohorts, BAG6 mutation is significantly associated with the RNA expression of many other genes, with 1,175 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAG6-associated genes across cancer lineages are RNA5SP411, PRELID3BP2, and HECW1-IT1. Each is linked with BAG6 in more than 2 cancer types. Because this analysis shows association rather than direction, both BAG6-to-partner and partner-to-BAG6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG6→partner) and Y-score (partner→BAG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP411 →	+0.420	+6.882	<.001	<.001	3	3
SKCM	PRELID3BP2 →	+0.032	+3.723	<.001	.009	3	3
LIHC	HECW1-IT1 →	+0.029	+7.169	<.001	<.001	3	2
LIHC	SNORD13P1 →	+0.357	+5.108	.001	.008	3	2
CESC	LINC01519 →	+0.018	+4.669	.004	.007	3	2
CESC	TRBV6-7 →	+0.296	+4.503	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,175 associations by consensus.

Exploration

BAG6 survival (RNA) · tumor vs normal (RNA) · all BAG6 data types