BAG4

Across TCGA cell cohorts, BAG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,943 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAG4-associated GO terms across cancer lineages are Interkinetic nuclear migration, Protein localization to chromosome, and Protein-DNA complex assembly. Each is linked with BAG4 in more than 13 cancer types. Because this analysis shows association rather than direction, both BAG4-to-partner and partner-to-BAG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interkinetic nuclear migration grouped by BAG4-low versus BAG4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BAG4→partner) and Y-score (partner→BAG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Interkinetic nuclear migration →	+0.117	+0.932	<.001	<.001	3	14
BLOOD_Lymphoma	Protein localization to chromosome →	+0.085	+0.811	<.001	<.001	3	13
LUNG_SCLC	Protein-DNA complex assembly →	+0.067	+0.973	.005	.001	3	13
URINARY_TRACT	Protein-DNA complex organization →	+0.064	+0.976	.001	.003	2	14
LUNG_NSCLC_LUSC	Negative regulation of sister chromatid cohesion →	+0.186	+1.472	.001	.001	3	13
LUNG_NSCLC_LUSC	Regulation of microtubule-based process →	+0.049	+0.867	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,943 associations by consensus.

Interkinetic nuclear migration by BAG4 expression — OVARY

Explore this box plot interactively →