BACH2

Across TCGA patient cohorts, BACH2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,740 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BACH2-associated genes across cancer lineages are ZNF660, TMEM169, and GRID1. Each is linked with BACH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BACH2-to-partner and partner-to-BACH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BACH2 versus ZNF660 in LUAD, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BACH2→partner) and Y-score (partner→BACH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF660 →	+0.648	+0.420	.001	.002	3	2
LUAD	TMEM169 →	+0.677	+0.599	.004	.002	3	2
LUAD	GRID1 →	+0.472	+0.397	.009	.007	3	2
LUAD	RN7SKP110 →	+1.050	+0.538	.004	.002	3	2
LUAD	RPL21P32 →	+1.024	+0.550	.004	<.001	3	2
LSCC	KRT8P44 →	+0.385	+0.490	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,740 associations by consensus.

BACH2 vs ZNF660 — LUAD

Explore this scatter interactively →