BACE1-AS

Across TCGA pan-cancer cohorts, BACE1-AS RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated BACE1-AS data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BACE1-AS RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BACE1-AS expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

ACC, LIHC, and HNSC are the cancer types where BACE1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.185	0.696	<.001	94	view →
LIHC	OS	Median	All	0.694	0.852	<.001	93	view →
HNSC	DFS	Quartile	IV	0.761	0.498	.001	47	view →
KIRC	DFS	Median	II,III,IV	0.445	0.602	.007	38	view →
DLBC	DFS	Quartile	All	0.573	1.000	.008	15	view →
READ	OS	Median	IV	0.861	0.564	.019	12	view →
THCA	DFS	Median	All	0.873	0.779	.007	10	view →
LUAD	DFS	Tertile	II,III,IV	0.615	0.815	.034	9	view →
PAAD	DFS	Median	All	0.478	0.245	.008	7	view →
KICH	DFS	Median	III,IV	0.462	1.000	.027	6	view →
SKCM	OS	Median	All	0.260	0.518	.003	6	view →
BLCA	OS	Median	III,IV	0.755	0.604	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

BACE1-AS–ACC (DFS)

Open the ACC breakdown →