BABAM1

Across TCGA patient cohorts, BABAM1 mutation is significantly associated with the RNA expression of many other genes, with 394 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BABAM1-associated genes across cancer lineages are CLIC4P1, RNA5SP413, and WFDC9. Each is linked with BABAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BABAM1-to-partner and partner-to-BABAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLIC4P1 grouped by BABAM1-low versus BABAM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BABAM1→partner) and Y-score (partner→BABAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLIC4P1 →	+0.156	+2.050	.008	.005	3	2
UCEC	RNA5SP413 →	+0.976	+2.084	<.001	.006	3	2
SKCM	WFDC9 →	+0.059	+4.867	<.001	.005	3	2
UCEC	MIR3661 →	+0.776	+2.327	<.001	.002	3	2
HNSC	RPL23AP39 →	+0.158	+5.241	<.001	.007	3	1
SKCM	OR8X1P →	+0.048	+5.080	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 394 associations by consensus.

CLIC4P1 by BABAM1 expression — UCEC

Explore this box plot interactively →