BABAM1

Across TCGA patient cohorts, BABAM1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BABAM1-associated genes across cancer lineages are HSP70, IGFBP2, and MYH11. Each is linked with BABAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BABAM1-to-partner and partner-to-BABAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSP70 grouped by BABAM1-low versus BABAM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BABAM1→partner) and Y-score (partner→BABAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSP70 →	-0.404	-2.990	.045	.036	3	1
UCEC	IGFBP2 →	-1.066	-2.321	.001	.035	3	1
UCEC	MYH11 →	+1.307	+2.321	.023	.035	3	1
UCEC	p62 Lck ligand →	+0.349	+3.459	.033	.005	3	1
UCEC	STAT5a →	+0.563	+2.321	.005	.035	3	1
UCEC	Caspase-8 →	-0.297	-3.143	.018	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

HSP70 by BABAM1 expression — UCEC

Explore this box plot interactively →