BABAM1

Across TCGA cell cohorts, BABAM1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BABAM1-associated genes across cancer lineages are CRYGC, ENPP6, and SSMEM1. Each is linked with BABAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BABAM1-to-partner and partner-to-BABAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGC grouped by BABAM1-low versus BABAM1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BABAM1→partner) and Y-score (partner→BABAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRYGC →	+0.026	+4.969	<.001	.003	3	1
LARGE_INTESTINE	ENPP6 →	+0.043	+4.115	<.001	.001	3	1
LARGE_INTESTINE	SSMEM1 →	+0.029	+4.029	<.001	.002	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	SPEM1 →	+0.110	+3.347	<.001	.005	3	1
LARGE_INTESTINE	ACTL7A →	+0.028	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CRYGC by BABAM1 expression — BLOOD_Leukemia

Explore this box plot interactively →