B9D2

Across TCGA cell cohorts, B9D2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B9D2-associated genes across cancer lineages are NAT8, SSMEM1, and OR10W1. Each is linked with B9D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B9D2-to-partner and partner-to-B9D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAT8 grouped by B9D2-low versus B9D2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B9D2→partner) and Y-score (partner→B9D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NAT8 →	+0.524	+3.443	.006	.009	3	1
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.029	.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+3.562	<.001	.002	3	1
LARGE_INTESTINE	HIGD2B →	+0.073	+3.724	<.001	.004	3	1
LARGE_INTESTINE	FAM153B →	+0.506	+3.618	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

NAT8 by B9D2 expression — LARGE_INTESTINE

Explore this box plot interactively →