B9D1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B9D1 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B9D1-associated genes across cancer lineages are DEFB103A, RNU6-41P, and MTND1P31. Each is linked with B9D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B9D1-to-partner and partner-to-B9D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB103A grouped by B9D1-low versus B9D1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B9D1→partner) and Y-score (partner→B9D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADEFB103A →+0.059+8.055<.001.00732
UCECRNU6-41P →+0.345+3.771<.001.00232
LGGMTND1P31 →+0.044+7.977<.001.00732
LGGMIR6792 →+0.477+7.977<.001.00732
COADCOX5BP8 →+0.235+4.308<.001.00932
COADPOMPP1 →+0.287+4.962<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

DEFB103A by B9D1 expression — BRCA

Box plot of DEFB103A in B9D1-low vs B9D1-high samples in BRCA.

Explore this box plot interactively →

Exploration