B4GAT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GAT1 mutation is significantly associated with the RNA expression of many other genes, with 391 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GAT1-associated genes across cancer lineages are SIGLEC27P, SNORD3G, and RNA5SP234. Each is linked with B4GAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GAT1-to-partner and partner-to-B4GAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC27P grouped by B4GAT1-low versus B4GAT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GAT1→partner) and Y-score (partner→B4GAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSIGLEC27P →+0.087+5.392<.001.00232
BLCASNORD3G →+0.419+5.411<.001.00532
BRCARNA5SP234 →+0.237+8.055<.001.00732
BLCARNF19BPY →+0.035+6.444<.001.00132
UCECKRTAP23-1 →+0.212+2.547.004.00932
UCECKRTAP20-3 →+0.090+4.601<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

SIGLEC27P by B4GAT1 expression — COAD

Box plot of SIGLEC27P in B4GAT1-low vs B4GAT1-high samples in COAD.

Explore this box plot interactively →

Exploration