B4GAT1

Across TCGA patient cohorts, B4GAT1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GAT1-associated genes across cancer lineages are eEF2, ERK2, and Heregulin. Each is linked with B4GAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GAT1-to-partner and partner-to-B4GAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by B4GAT1-low versus B4GAT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GAT1→partner) and Y-score (partner→B4GAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.370	+2.321	.039	.035	3	1
UCEC	ERK2 →	+0.228	+2.321	.018	.035	3	1
UCEC	Heregulin →	-0.134	-3.000	.031	.036	3	1
UCEC	MSH6 →	-0.476	-2.321	.004	.035	3	1
UCEC	VHL →	-0.880	-3.459	.009	.005	3	1
UCEC	Cyclin-B1 →	+0.588	+2.321	.037	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

eEF2 by B4GAT1 expression — UCEC

Explore this box plot interactively →