B4GALT7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, B4GALT7 protein abundance is significantly associated with the go_rna of many other GO terms, with 571 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible B4GALT7-associated GO terms across cancer lineages are Negative regulation of macrophage differentiation, Negative regulation of innate immune response, and Positive regulation of transcription by RNA polymerase III. Each is linked with B4GALT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT7-to-partner and partner-to-B4GALT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of macrophage differentiation grouped by B4GALT7-low versus B4GALT7-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT7→partner) and Y-score (partner→B4GALT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNegative regulation of macrophage differentiation →-0.185-1.891.002<.00131
BLOOD_LymphomaNegative regulation of innate immune response →-0.119-2.235.001.00131
BLOOD_LymphomaPositive regulation of transcription by RNA polymerase III →-0.063-1.767.007.00431
BLOOD_LymphomaPositive regulation by virus of viral protein levels in host cell →-0.100-1.733.009.00131
BLOOD_LymphomaPhospholipid dephosphorylation →-0.032-2.009.005<.00131
BLOOD_LymphomaNegative regulation of melanin biosynthetic process →-0.178-1.783<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 571 associations by consensus.

Negative regulation of macrophage differentiation by B4GALT7 expression — BLOOD_Lymphoma

Box plot of Negative regulation of macrophage differentiation in B4GALT7-low vs B4GALT7-high samples in BLOOD_Lymphoma.

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