B4GALT6

Across TCGA patient cohorts, B4GALT6 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT6-associated genes across cancer lineages are Annexin-1, C-Raf, and 14-3-3_beta. Each is linked with B4GALT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT6-to-partner and partner-to-B4GALT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by B4GALT6-low versus B4GALT6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT6→partner) and Y-score (partner→B4GALT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.477	+2.019	.010	.017	3	2
UCEC	C-Raf →	+0.124	+1.906	.014	.015	3	2
UCEC	14-3-3_beta →	-0.079	-2.088	.026	.016	3	1
UCEC	EGFR_pY1068 →	-0.267	-3.000	.002	<.001	3	1
UCEC	ERK2 →	+0.153	+1.584	.024	.034	3	1
UCEC	Gab2 →	+0.260	+1.362	.039	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Annexin-1 by B4GALT6 expression — UCEC

Explore this box plot interactively →