B4GALT6

Across TCGA cell cohorts, B4GALT6 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible B4GALT6-associated genes across cancer lineages are TAFA1, CENPVL3, and OOSP4A. Each is linked with B4GALT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT6-to-partner and partner-to-B4GALT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by B4GALT6-low versus B4GALT6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT6→partner) and Y-score (partner→B4GALT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAFA1 →	+0.329	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	CENPVL3 →	+0.322	+3.920	<.001	.005	3	1
LARGE_INTESTINE	OOSP4A →	+0.076	+3.793	.006	.007	3	1
LARGE_INTESTINE	NEXMIF →	+0.319	+4.196	<.001	.002	3	1
BLOOD_Leukemia	LGI1 →	+0.091	+4.539	<.001	.007	3	1
BLOOD_Leukemia	MS4A5 →	+0.079	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TAFA1 by B4GALT6 expression — LARGE_INTESTINE

Explore this box plot interactively →