B4GALT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GALT2 mutation is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT2-associated genes across cancer lineages are RNU6-980P, RNA5SP261, and TAAR1. Each is linked with B4GALT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT2-to-partner and partner-to-B4GALT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-980P grouped by B4GALT2-low versus B4GALT2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT2→partner) and Y-score (partner→B4GALT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU6-980P →+0.549+5.015<.001.00932
STADRNA5SP261 →+0.729+5.026<.001.00932
COADTAAR1 →+0.569+3.681<.001.00331
COADHOXC5 →+0.261+3.627<.001.00831
UCECLIN7C →+0.522+1.786.003.00831
UCECSERPING1 →-0.814-3.553.002.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

RNU6-980P by B4GALT2 expression — HNSC

Box plot of RNU6-980P in B4GALT2-low vs B4GALT2-high samples in HNSC.

Explore this box plot interactively →

Exploration