B4GALT2

Across TCGA patient cohorts, B4GALT2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT2-associated genes across cancer lineages are A-Raf_pS299, Akt_pT308, and C-Raf. Each is linked with B4GALT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT2-to-partner and partner-to-B4GALT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by B4GALT2-low versus B4GALT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT2→partner) and Y-score (partner→B4GALT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.127	-2.459	.012	.019	3	2
UCEC	Akt_pT308 →	+0.557	+2.222	.037	.011	3	2
UCEC	C-Raf →	+0.176	+2.700	.003	.006	3	2
UCEC	eIF4E →	+0.199	+2.321	.026	.034	3	1
UCEC	ER-alpha_pS118 →	+0.351	+2.183	.021	.033	3	1
UCEC	Fibronectin →	-0.329	-1.700	.018	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

A-Raf_pS299 by B4GALT2 expression — UCEC

Explore this box plot interactively →