B4GALT2

Across TCGA cell cohorts, B4GALT2 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B4GALT2-associated genes across cancer lineages are SCGB1C1, SCGB1C2, and CFHR2. Each is linked with B4GALT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT2-to-partner and partner-to-B4GALT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C1 grouped by B4GALT2-low versus B4GALT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT2→partner) and Y-score (partner→B4GALT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SCGB1C1 →	+0.133	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	SCGB1C2 →	+0.087	+5.247	<.001	.001	3	1
CNS	CFHR2 →	+0.076	+6.357	<.001	<.001	3	1
LUNG_NSCLC_LUAD	GZMH →	+0.060	+4.887	<.001	.009	3	1
LARGE_INTESTINE	SERAC1 →	+0.731	+3.067	.001	.009	3	1
LARGE_INTESTINE	PTH2R →	+0.751	+2.781	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

SCGB1C1 by B4GALT2 expression — BLOOD_Lymphoma

Explore this box plot interactively →