B4GALT1

Across TCGA pan-cancer cohorts, B4GALT1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated B4GALT1 data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher B4GALT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated B4GALT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

PDAC, GBM, and LSCC are the cancer types where B4GALT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.692	0.866	.006	39	view →
GBM	DFS	Tertile	All	0.234	0.450	.005	15	view →
LSCC	DFS	Quartile	All	0.599	0.898	.003	14	view →
CCRCC	OS	Tertile	All	0.516	1.000	.003	14	view →
LUAD	DFS	Median	All	0.877	0.954	.004	7	view →
HNSC	DFS	Median	III,IV	0.915	0.678	.011	6	view →
UCEC	DFS	Tertile	All	0.913	0.769	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

B4GALT1–PDAC (DFS)

Open the PDAC breakdown →