B4GALNT3

Across TCGA patient cohorts, B4GALNT3 mutation is significantly associated with the RNA expression of many other genes, with 2,132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT3-associated genes across cancer lineages are PSMC3IP, ZWILCH, and CCDC43. Each is linked with B4GALNT3 in more than 3 cancer types. Because this analysis shows association rather than direction, both B4GALNT3-to-partner and partner-to-B4GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMC3IP grouped by B4GALNT3-low versus B4GALNT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT3→partner) and Y-score (partner→B4GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMC3IP →	+0.549	+2.193	<.001	.001	3	4
BLCA	ZWILCH →	+0.694	+3.202	.001	.009	3	3
UCEC	CCDC43 →	+0.417	+3.021	.003	<.001	3	3
UCEC	EMC3-AS1 →	+0.405	+1.895	.004	.001	3	3
UCEC	ZNF724 →	+0.491	+1.773	.003	.008	3	3
UCEC	RPL31P47 →	+0.243	+1.800	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,132 associations by consensus.

PSMC3IP by B4GALNT3 expression — UCEC

Explore this box plot interactively →