B4GALNT3

Across TCGA patient cohorts, B4GALNT3 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT3-associated genes across cancer lineages are IGFBP2, A-Raf_pS299, and FoxM1. Each is linked with B4GALNT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT3-to-partner and partner-to-B4GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by B4GALNT3-low versus B4GALNT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT3→partner) and Y-score (partner→B4GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.618	-1.502	.009	.030	3	2
UCEC	A-Raf_pS299 →	-0.107	-3.169	.015	.018	3	2
UCEC	FoxM1 →	+0.233	+1.502	.014	.030	3	2
UCEC	p53 →	-0.294	-2.700	.038	.005	3	2
UCEC	VHL →	-1.051	-2.247	<.001	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.546	+2.584	.012	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

IGFBP2 by B4GALNT3 expression — UCEC

Explore this box plot interactively →