B4GALNT3

Across TCGA cell cohorts, B4GALNT3 mutation is significantly associated with the RNA expression of many other genes, with 1,030 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B4GALNT3-associated genes across cancer lineages are C12orf57, MAGEB4, and ASPHD2. Each is linked with B4GALNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALNT3-to-partner and partner-to-B4GALNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf57 grouped by B4GALNT3-low versus B4GALNT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT3→partner) and Y-score (partner→B4GALNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C12orf57 →	+0.792	+3.321	.002	.003	3	2
LARGE_INTESTINE	MAGEB4 →	+0.007	+2.678	.001	.005	3	2
LARGE_INTESTINE	ASPHD2 →	+0.781	+2.502	<.001	.005	3	2
LARGE_INTESTINE	NHSL1 →	+1.025	+3.386	<.001	.001	3	2
LARGE_INTESTINE	ATF5 →	+0.930	+2.502	.007	.005	3	2
LARGE_INTESTINE	SELENOM →	+1.868	+2.502	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,030 associations by consensus.

C12orf57 by B4GALNT3 expression — LARGE_INTESTINE

Explore this box plot interactively →