Across TCGA pan-cancer cohorts, B3GNTL1P2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of B3GNTL1P2’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where B3GNTL1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types B3GNTL1P2 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
COAD, KIRP, and KIRC are the cancer types where B3GNTL1P2 tumor–normal differential expression is most reproducible.