B3GNTL1

Across TCGA patient cohorts, B3GNTL1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNTL1-associated genes across cancer lineages are ERK2, Heregulin, and p62 Lck ligand. Each is linked with B3GNTL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNTL1-to-partner and partner-to-B3GNTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by B3GNTL1-low versus B3GNTL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNTL1→partner) and Y-score (partner→B3GNTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.212	+3.321	.011	.009	3	1
UCEC	Heregulin →	-0.134	-2.584	.012	.010	3	1
UCEC	p62 Lck ligand →	+0.483	+3.459	<.001	.005	3	1
UCEC	PARP_cleaved →	-0.264	-3.169	.049	.018	3	1
UCEC	P-Cadherin →	-0.128	-2.999	.043	.035	3	1
UCEC	Rab25 →	-0.527	-3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ERK2 by B3GNTL1 expression — UCEC

Explore this box plot interactively →