B3GNTL1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, B3GNTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,597 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible B3GNTL1-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of epinephrine secretion, and Regulation of telomere maintenance. Each is linked with B3GNTL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both B3GNTL1-to-partner and partner-to-B3GNTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by B3GNTL1-low versus B3GNTL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNTL1→partner) and Y-score (partner→B3GNTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.158+0.909.001.002310
URINARY_TRACTRegulation of epinephrine secretion →+1.620+1.119<.001.00639
UPPER_AERODIGESTIVE_TRACTRegulation of telomere maintenance →+0.071+1.051<.001<.00139
UPPER_AERODIGESTIVE_TRACTNegative regulation of telomere maintenance →+0.097+1.197<.001<.00139
SOFT_TISSUEDe novo centriole assembly →+0.132+0.618<.001.00138
SOFT_TISSUEDe novo centriole assembly involved in multi-ciliated epithelial cell differentiation →+0.132+0.674<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,597 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by B3GNTL1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Positive regulation of intracellular steroid hormone receptor signaling pathway in B3GNTL1-low vs B3GNTL1-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration